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Novel Peptide Derived from Human Apolipoprotein E Inhibits Hepatitis C Virus Entry

Reference #: 00885 The University of South Carolina is offering licensing opportunities for this novel method of blocking and/or treating Hepatitis C Virus. Invention Description: This invention is a human apolipoprotein E (apoE) peptide, designated hEP. hEP blocks Hepatitis C Virus (HCV) entry into hepatocytes. This peptide specifically blocks...

Published: 3/1/2018 | Inventor(s): Daping Fan, Tianyi Wang, Shufeng Liu

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Category(s): Biomedical and Life Sciences

Structural Analysis of the CDK4/cyclin D1 Substrate Recognition Site and Basis for p27 and Inhibitor Binding

Reference #: 00829 Invention Description: An alternative strategy for inhibition of the cyclin dependent kinases in anti-tumor drug discovery is afforded through the substrate recruitment site on the cyclin positive regulatory subunit. This approach offers the potential for generating cell cycle-specific CDK inhibitors and to reduce the inhibition...

Published: 9/2/2022 | Inventor(s): Campbell Mcinnes, Shu Liu

Keywords(s):

Category(s): Biomedical and Life Sciences