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Nepenthes GDSL Lipase to Treat Gut Lipid Malabsorption and Atrophy
Reference #: 1718 The University of South Carolina is offering licensing opportunities for Nepenthes GDSL Lipase to Treat Gut Lipid Malabsorption and Atrophy. Background: The absorption of dietary lipids in the small intestine is a fundamental biological process central to maintaining energy balances in tissues. Atrophy occurs when the energetic...
Published: 9/18/2024
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Inventor(s):
Jason Kubinak
Keywords(s):
Category(s):
Health Sciences
,
Biomedical and Life Sciences
Neural repair through inhibition of Reg3A signaling
Reference #: 1677 The University of South Carolina is offering licensing opportunities for Neural repair through inhibition of Reg3A signaling. Background: Human peripheral nerve regeneration is rarely successful when the nerve's axons must regrow more than 5-6 cm. By the time the regenerating axons in the nerve get past 5-6 cm, the environment...
Published: 9/18/2024
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Inventor(s):
Jeffery Twiss
,
Courtney Buchanan
,
Jinyoung Lee
,
Lauren Vaughn
,
Ashley Kalinski
Keywords(s):
Category(s):
Biomedical and Life Sciences
,
Health Sciences
Engineering Immune Responses with Programmable Transcription Factors
Reference #: 1699 The University of South Carolina is offering licensing opportunities for Engineering Immune Responses with Programmable Transcription Factors. Background: The regulation immune activation pathways are the bedrock of immunotherapy treatments for cancer and infectious diseases. Strategies for activation typically include administering...
Published: 9/18/2024
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Inventor(s):
Nicholas Truex
,
Lydia Pless
,
Hannah Ponder
,
Olivia Sherron
,
Ashley King
,
Victoria Beato
Keywords(s):
Category(s):
Biomedical and Life Sciences
,
Health Sciences
Novel imidazothiazoles inhibiting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO)
Reference #: 1706 The University of South Carolina is offering licensing opportunities for Novel imidazothiazoles inhibiting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO). Background: The kynurenine pathway (KP) is involved in the modulation of many biological and physiological processes including immune response and neurotransmission....
Published: 10/7/2024
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Inventor(s):
Yangmei Li
Keywords(s):
Category(s):
Biomedical and Life Sciences
,
Health Sciences
A CCL8-based cytotoxic analog for cancer management
Reference #: 1721 The University of South Carolina is offering licensing opportunities for A CCL8-based cytotoxic analog for cancer management. Background: Deregulation of cytokine and chemokine networks is common in various malignancies and other pathologies and has causative role in disease progression. Despite however their acknowledged role in...
Published: 9/26/2024
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Inventor(s):
Hippokratis Kiaris
,
Bernardo Chavez
Keywords(s):
Category(s):
Health Sciences
,
Biomedical and Life Sciences
An amino acid hybrid of aCGRP to treat cardiovascular disease
Reference #: 01645 The University of South Carolina is offering licensing opportunities for An Amino Acid Hybrid of a CGRP to Treat Cardiovascular Disease. Background: Heart failure is a chronic condition affecting millions of people worldwide, often leading to reduced lifespan and poor quality of life. The American Heart Association (AHA) estimates...
Published: 8/29/2024
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Inventor(s):
Jay Potts
,
Ambrish Kumar
,
Donald Dipette
Keywords(s):
Category(s):
Biomedical and Life Sciences
,
Health Sciences
Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications
Reference #: 1685 The University of South Carolina is offering licensing opportunities for Cyclopropanol as a bioorthogonal warhead for electrochemically controlled bioconjugation applications. Background: Bioconjugation techniques play an important role in modern chemical biology and biomedical sciences, such as protein drug stabilization, target...
Published: 6/12/2024
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Inventor(s):
Qian Wang
,
Shan Hu
Keywords(s):
Category(s):
Biomedical and Life Sciences
,
Health Sciences
Novel treatment for pseudomyxoma peritonei
Reference #: 1692 The University of South Carolina is offering licensing opportunities for Novel treatment for pseudomyxoma peritonei. Background: Pseudomyxoma peritonei (PMP) is a rare cancer, which originates as an appendiceal neoplasm. Due to its usually poor vascularization and floating as nodules, PMP spreads easily to the peritoneal cavity,...
Published: 6/11/2024
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Inventor(s):
Jie Li
,
Daping Fan
,
Hexin Chen
,
Traci Testerman
Keywords(s):
Category(s):
Biomedical and Life Sciences
,
Health Sciences
Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application
Reference #: 1678 The University of South Carolina is offering licensing opportunities for Immunomodulating Activities of Alistipes and Its Metabolites: Mechanism and Application. Background: The gut microbiota plays a key role in health and disease. The balance between beneficial genera (such as Alistipes and Odoribacter) and harmful species (such...
Published: 8/13/2024
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Inventor(s):
Jie Li
,
Hexin Chen
,
Daping Fan
Keywords(s):
Category(s):
Biomedical and Life Sciences
,
Health Sciences
Nepenthes prolyl endopeptidases to suppress gluten sensitivity in humans
Reference #: 1673 The University of South Carolina is offering licensing opportunities for Nepenthes prolyl endopeptidases to suppress gluten sensitivity in humans. Background: It is currently estimated that 5% of the world's population suffers from gluten-related disorders, though this number is considered a gross underestimate due to the difficulties...
Published: 6/11/2024
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Inventor(s):
Jason Kubinak
Keywords(s):
Category(s):
Biomedical and Life Sciences
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