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A CCL8-based cytotoxic analog for cancer management

Reference #: 1721 The University of South Carolina is offering licensing opportunities for A CCL8-based cytotoxic analog for cancer management. Background: Deregulation of cytokine and chemokine networks is common in various malignancies and other pathologies and has causative role in disease progression. Despite however their acknowledged role in...

Published: 12/17/2024 | Inventor(s): Hippokratis Kiaris, Bernardo Chavez

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Category(s): Health Sciences, Biomedical and Life Sciences

Nepenthes GDSL Lipase to Treat Gut Lipid Malabsorption and Atrophy

Reference #: 1718 The University of South Carolina is offering licensing opportunities for Nepenthes GDSL Lipase to Treat Gut Lipid Malabsorption and Atrophy. Background: The absorption of dietary lipids in the small intestine is a fundamental biological process central to maintaining energy balances in tissues. Atrophy occurs when the energetic...

Published: 12/17/2024 | Inventor(s): Jason Kubinak

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Category(s): Health Sciences, Biomedical and Life Sciences

Naphthoic Acid-Derived Polymers as Antimicrobial Agents

Reference #: 1710 The University of South Carolina is offering licensing opportunities for Naphthoic Acid-Derived Polymers as Antimicrobial Agents. Background: In the last couple of decades, polymers have been utilized in the medicinal industry into various applications such as drug carriers and substrates, enzyme inhibitors, and preservatives, due...

Published: 4/8/2025 | Inventor(s): Chuanbing Tang, Leman Kurnaz

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Category(s): Biomedical and Life Sciences, Chemistry and Biochemistry

Novel imidazothiazoles inhibiting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO)

Reference #: 1706 The University of South Carolina is offering licensing opportunities for Novel imidazothiazoles inhibiting indoleamine 2,3-dioxygenase 1 (IDO1) and tryptophan 2,3-dioxygenase (TDO). Background: The kynurenine pathway (KP) is involved in the modulation of many biological and physiological processes including immune response and neurotransmission....

Published: 12/17/2024 | Inventor(s): Yangmei Li

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Category(s): Biomedical and Life Sciences, Health Sciences

Aminergic phytocannabinoids derivatives as multi-target agents for Neurological disorders

Reference #: 1729 The University of South Carolina is offering licensing opportunities for Aminergic phytocannabinoids derivatives as multi-target agents for neurological disorders. Background: The medicinal properties of certain aminergic cannabinoid derivatives are currently being explored, but preliminary data shows they may possess potential...

Published: 2/25/2025 | Inventor(s): Juan Francisco Leon Oyola, Zachary Stryker

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Category(s): Biomedical and Life Sciences, Health Sciences

Design of Biosensor with high sensitivity and selectivity

Reference #: 1687 The University of South Carolina is offering licensing opportunities for Design of Biosensor with high sensitivity and selectivity. Background: Biosensors have become a potent tool that is widely used for health care, environmental and food safety monitoring, and all the way for disease diagnostics. The early diagnosis of diseases...

Published: 2/25/2025 | Inventor(s): Sourav Banerjee, Debdyuti Mandal

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Category(s): Health Sciences, Biomedical and Life Sciences, Software and Computing, Engineering and Physical Sciences, Advanced Materials

Predicting biomaterial-implant surgical outcome using medical record and blood-cytokine data

Reference #: 1680 The University of South Carolina is offering licensing opportunities for Predicting biomaterial-implant surgical outcome using medical record and blood-cytokine data. Background: Pelvic organ prolapse (POP), defined as symptomatic descent of the vagina and surrounding pelvic organs, affects approximately 50% of parous women and...

Published: 11/19/2024 | Inventor(s): Melissa Moss, Mihyun Waugh, Nicholas Boltin, Lauren Wolf, Ronnie Horner, Thomas Wheeler, Richard Goodwin, Robert Gower

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Category(s): Biomedical and Life Sciences, Advanced Materials, Health Sciences, Chemistry and Biochemistry

Neural repair through inhibition of Reg3A signaling

Reference #: 1677 The University of South Carolina is offering licensing opportunities for Neural repair through inhibition of Reg3A signaling. Background: Human peripheral nerve regeneration is rarely successful when the nerve's axons must regrow more than 5-6 cm. By the time the regenerating axons in the nerve get past 5-6 cm, the environment...

Published: 4/18/2025 | Inventor(s): Jeffery Twiss, Courtney Buchanan, Jinyoung Lee, Lauren Vaughn, Ashley Kalinski

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Category(s): Biomedical and Life Sciences, Health Sciences

Engineering Immune Responses with Programmable Transcription Factors

Reference #: 1699 The University of South Carolina is offering licensing opportunities for Engineering Immune Responses with Programmable Transcription Factors. Background: The regulation immune activation pathways are the bedrock of immunotherapy treatments for cancer and infectious diseases. Strategies for activation typically include administering...

Published: 4/23/2025 | Inventor(s): Nicholas Truex, Lydia Pless, Hannah Ponder, Olivia Sherron, Ashley King, Victoria Beato

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Category(s): Biomedical and Life Sciences, Health Sciences

An amino acid hybrid of aCGRP to treat cardiovascular disease

Reference #: 01645 The University of South Carolina is offering licensing opportunities for An Amino Acid Hybrid of a CGRP to Treat Cardiovascular Disease. Background: Heart failure is a chronic condition affecting millions of people worldwide, often leading to reduced lifespan and poor quality of life. The American Heart Association (AHA) estimates...

Published: 8/29/2024 | Inventor(s): Jay Potts, Ambrish Kumar, Donald Dipette

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Category(s): Biomedical and Life Sciences, Health Sciences

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