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Misty Plasma Dielectric Barrier Discharge Plasma System for Disinfection

Reference #: 01600 The University of South Carolina is offering licensing opportunities for Misty Plasma Dielectric Barrier Discharge Plasma System for Disinfection Background: Approximately 1.7 million healthcare-associated infections occur each year in the U.S., killing 98,000 patients. COVID-19 has revealed further weaknesses in the preparedness...

Published: 4/2/2024 | Inventor(s): Malik Tahiyat, Tanvir Farouk, Shamia Hoque, Traci Testerman

Keywords(s): cold atmospheric plasma, dielectric barrier discharge, disinfection, sterilization, water vapor plasma

Category(s): Biomedical and Life Sciences, Health Sciences

The value of microRNA-155 in breast cancer prognosis and treatment

Reference #: 01608 The University of South Carolina is offering licensing opportunities for The value of microRNA-155 in breast cancer prognosis and treatment Background: In the US in 2021, there were an estimated 281,550 new cases of invasive breast cancer diagnosed in women; 2,650 cases diagnosed in men. An estimated 44,130 breast cancer deaths...

Published: 4/2/2024 | Inventor(s): Daping Fan, Junfeng Wang,

Keywords(s): breast cancer, immune therapy, microRNA, microRNA-155, predictive biomarker, prognosis

Category(s): Health Sciences, Biomedical and Life Sciences

Click Chemistry Amplified Nanopore Assay for Ultrasensitive Quantification of Proteins

Reference #: 01610 The University of South Carolina is offering licensing opportunities for Click Chemistry Amplified Nanopore Assay for Ultrasensitive Quantification of Proteins Background: Despite major advances in HIV testing, ultrasensitive detection of early infection remains a key challenge, especially for the viral capsid protein p24, which...

Published: 2/2/2024 | Inventor(s): Chang Liu

Keywords(s): antibody, antigen, assay, biosensor, detection, diagnostic, HIV, nanopore, protein, quantification

Category(s): Biomedical and Life Sciences, Health Sciences

Abbapolins as Inhibitors and Degraders of Polo-Like Kinases

Reference #: 01593 The University of South Carolina is offering licensing opportunities for Abbapolins as Inhibitors and Degraders of Polo-Like Kinases Background: There are no effective treatments for castration-resistant prostate cancers as all current therapies eventually fail. Invention Description: Novel chemicals called abbapolins are described...

Published: 4/2/2024 | Inventor(s): Campbell Mcinnes, Michael Wyatt, Danda Chapagai, Jessy Stafford, Gursanker Ramamoorthy

Keywords(s): abbapolin, drug discovery, peptide, Polo Like Kinase

Category(s): Biomedical and Life Sciences, Health Sciences

Phospholipid Presenting Particles for Cell Targeting in Therapy and Diagnostics

Reference #: 01594 The University of South Carolina is offering licensing opportunities for Phospholipid Presenting Particles for Cell Targeting in Therapy and Diagnostics Background: Current FDA approved controlled/extended-release formulations based on polyesters such as polylactic acid, poly(lactide-co-glycolide), and polycaprolactone do not benefit...

Published: 3/27/2023 | Inventor(s): Kidochukwu Atube, Robert Gower

Keywords(s): cell targeting, drug delivery, emulsion, microparticles, phospholipid, poly(lactide-co-glycolide), polymer particles

Category(s): Biomedical and Life Sciences, Health Sciences

Panaxynol as a new agent for cancer prevention and treatment

Reference #: 01618 The University of South Carolina is offering licensing opportunities for Panaxynol as a new agent for cancer prevention and treatment Background: National costs for cancer care were estimated to be $208.9 billion in 2020; particularly for colorectal cancer (CRC), the economic burden in the U.S. is estimated to be over $24 billion...

Published: 3/21/2024 | Inventor(s): Angela Murphy, Lorne Hofseth

Keywords(s): cancer, cancer prevention, cancer treatment, Colon cancer, Natural product, polyps

Category(s): Biomedical and Life Sciences, Health Sciences

Water based hypotonic lysis method for Adeno Associated Virus purification

Reference #: 01595 The University of South Carolina is offering licensing opportunities for a hypotonic-solution-based cell lysis method for Adeno Associated Virus purification Background: Adeno Associated Viral vectors have become popular candidates for gene therapy but suffer the drawback of requiring a time-consuming freeze-thaw (FT) lysis or...

Published: 4/2/2024 | Inventor(s): Sujit Pujhari, Ronald Smithwick

Keywords(s): adeno associated virus, gene therapy, hypotonic solution, solute concentration, viral vectors, water potential

Category(s): Health Sciences, Biomedical and Life Sciences

Temperature Responsive Cell Culture Platform for Mechanobiological Manipulation

Reference #: 01436 The University of South Carolina is offering licensing opportunities for Temperature Responsive Cell Culture Platform for Mechanobiological Manipulation Background: The invention pertains to a swellable platform with surface microwells of various shapes that can encapsulate and systematically apply mechanical pressure on cells....

Published: 9/4/2022 | Inventor(s): Ehsan Jabbarzadeh, Christopher Wu

Keywords(s): Antigen uptake, Cell culture platform, Cell secretome, Cellular Engineering, drug delivery, drug discovery, Gene transfection, Intracellular delivery, Mechanobiology, Mechanostimulation, PNIPAM

Category(s): Health Sciences, Biomedical and Life Sciences, Chemistry and Biochemistry

Tyrosine and resveratrol derivatives as novel modulators of cellular serine-ADP-ribosylation

Reference #: 01578 The University of South Carolina is offering licensing opportunities for Tyrosine and resveratrol derivatives as novel modulators of cellular serine-ADP-ribosylation Background: Currently, there are no molecules that specifically inhibit only serine-ADP-ribosylation without affecting global ADP-ribosylation. Invention Description: We...

Published: 11/7/2023 | Inventor(s): Sajish Mathew

Keywords(s): PARP inhibitors

Category(s): Health Sciences, Biomedical and Life Sciences

Use of delta 8 THC to treat inflammatory and autoimmune diseases

Reference #: 01583 The University of South Carolina is offering licensing opportunities for Use of delta 8 THC to treat inflammatory and autoimmune diseases Background: There are millions of people who suffer from debilitating inflammatory and autoimmune diseases against which there is no cure. Delta-8 THC is present in small quantity in cannabis...

Published: 10/26/2023 | Inventor(s): Prakash Nagarkatti, Mitzi Nagarkatti, Khadija Kakar

Keywords(s): anti-inflammatory biotech, anti-inflammatory pharma, autoimmune diseases, cannabinoids, inflammation

Category(s): Biomedical and Life Sciences, Health Sciences

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