Search Results - esmaiel+jabbari

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Regenerative Tissue-Mimetic Multilayer Fused Microgel-Cell Construct

Reference #: 01470 The University of South Carolina is offering licensing opportunities for Regenerative Tissue-Mimetic Multilayer Fused Microgel-Cell Construct Background: Tissue engineering aims to make cellular constructs for implantation in an injured tissue defect in a human patient to restore, maintain, repair, regenerate or improve the function...

Published: 8/21/2024 | Inventor(s): Esmaiel Jabbari

Keywords(s): Articular cartilage injury, articular cartilage microcarriers, articular cartilage mimetic cellular construct, articular cartilage regeneration, articular cartilage zonal-mimetic scaffold, cellular construct, cellular tissue construct, decellularized articular cartilage microcarrier, mesenchymal stem cells, microgels for cell expansion, multilayer cellular construct, regeneration of zonal structure of articular cartilage, stem cell expansion, tissue scaffold

Category(s): Biomedical and Life Sciences, Health Sciences

Enzymatically Cleavable Self Assembled Nanoparticles for Morphogen Delivery

Reference #: 01350 The University of South Carolina is offering licensing opportunities for Enzymatically Cleavable Self-Assembled Nanoparticles for Morphogen Deliver Background: There is a continuing need to develop approaches for controlled release of morphogens, which control cell shape, in applications such as tissue regeneration. While metal...

Published: 6/14/2023 | Inventor(s): Esmaiel Jabbari

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Category(s): Biomedical and Life Sciences, Engineering and Physical Sciences, Nanotechnology, Health Sciences

Digested Decellularized Tissue as Microcarrier for Cell Culture and Expansion

Reference #: 01345The University of South Carolina is offering licensing opportunities for Digested Decellularized Tissue as Microcarrier for Cell Culture and ExpansionBackground:Cells in vivo reside within an interconnected 3D structure. Conversely, cells seeded on 2D culture plates or 3D suspended microbead- or microcarrier-based tissue culture are...

Published: 5/27/2021 | Inventor(s): Esmaiel Jabbari

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Category(s): Chemistry and Biochemistry, Engineering and Physical Sciences, Biomedical and Life Sciences, Health Sciences

Engineered Matrix for Enriching Malignant Cancer Stem Cells

Reference #: 01067 The University of South Carolina is offering licensing opportunities for a novel system for testing cancer drugs. Invention Description: Cancer recurrence or relapse is related to a very small population of highly-malignant and metastasizing cancer stem cells that have the ability initiate, propagate, and maintain the cancer tissue....

Published: 5/27/2021 | Inventor(s): Esmaiel Jabbari

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Category(s): Biomedical and Life Sciences, Health Sciences

Macrophage Enabled 3D Enrichment of Cancer Stem Cells

Reference #: 01261The University of South Carolina is offering licensing opportunities for using a 3D cell culture system can be used to test cancer drugs against the most aggressive and malignant cancer cell populations.Background:A major contributing factor to mortality in cancer patients is relapse (after surgery or therapy) and developing resistance...

Published: 3/4/2024 | Inventor(s): Esmaiel Jabbari

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Category(s): Engineering and Physical Sciences, Health Sciences, Biomedical and Life Sciences, Advanced Materials

Drug Uptake by Cancer Stem Cells via Conjugation Silica Nanoparticles

Reference #1267:The University of South Carolina is offering licensing opportunities for a novel two part drug therapy for cancer cells with conjugation silica nanoparticles.Background:More than 12 million new cancer cases are diagnosed worldwide each year, with an estimated 8 million deaths occurring in the same year. A major contributing factor to...

Published: 6/7/2021 | Inventor(s): Esmaiel Jabbari

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Category(s): Nanotechnology, Health Sciences, Biomedical and Life Sciences, Chemistry and Biochemistry

Drug Conjugated Nanogels in Microcapsule for Delayed Sustained Protein Delivery

Reference #: 01255The University of South Carolina is offering licensing opportunities for an innovative approach to synthesize a nanogels-in-microparticle delivery system with delayed and sustained release of protein or peptide-based biologiocally active agents.Background:In many medical applications, drugs, peptides, proteins, morphogens, cytokines,...

Published: 8/10/2021 | Inventor(s): Esmaiel Jabbari

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Category(s): Nanotechnology, Chemistry and Biochemistry, Health Sciences, Advanced Materials

Composition for In Situ Zonal Regeneration of Articular Cartilage

Reference #: 01259The University of South Carolina is offering licensing opportunities for using therapies that mimic the regeneration of the zonal organization of articular cartilage.Background:Approximately 12% of all osteoarthritis (OA) cases are caused by post-traumatic osteoarthritis (PTOA). About 3.5 million individuals in US suffer from PTOA...

Published: 7/30/2021 | Inventor(s): Esmaiel Jabbari

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Category(s): Chemistry and Biochemistry, Biomedical and Life Sciences, Health Sciences

KeratATE Three-Dimensional Cell Culture System

Reference #: 01250The University of South Carolina is offering licensing opportunities for access to knowledge about a 3D biomimetic/biologic, trypsin-degradable cell culture system.Background:Mammalian cells are traditionally cultured and expanded on 2D cell culture flasks. However, the 2D culture flasks do not mimic the cell environment in vivo, leading...

Published: 5/27/2021 | Inventor(s): Esmaiel Jabbari

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Category(s): Advanced Materials, Biomedical and Life Sciences, Chemistry and Biochemistry

Photocrosslinkable Keratin-based Hydrogel for Cell Encapsulation

Reference #: 01216The University of South Carolina is offering licensing opportunities for the preparation of a modified keratin from poultry feathers for improving material properties. Background:Hydrogels are used extensively as matrices for delivery and immobilization of stem cells to the site of defect in soft tissue regeneration. They resemble...

Published: 5/27/2021 | Inventor(s): Esmaiel Jabbari

Keywords(s):

Category(s): Advanced Materials, Biomedical and Life Sciences, Health Sciences

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