Description:
Reference #: 1687
The University of South Carolina is offering licensing opportunities for Design of Biosensor with high sensitivity and selectivity.
Background:
Biosensors have become a potent tool that is widely used for health care, environmental and food safety monitoring, and all the way for disease diagnostics. The early diagnosis of diseases can enhance preventive measures, increase the curability of the disease, and reduce healthcare costs. Although there are many conventional biosensors, they often suffer challenges in terms of sensitivity, detection time, and expenses. For example, conventional surface acoustic waves (SAW)-grade biosensors are effective, but they often suffer sensitivity challenges leading to false-negatives.
Invention Description:
This invention is an innovative tone burst interdigitated electrodes (TB-IDT)-based biosensing that utilizes a unique fashion of surface acoustic waves technique for the biosensing phenomena. The TB-IDT consists of varied amplitude and width of the electrodes over the length that covers a wider range of frequency and amplitude access enhancing the sensitivity by many folds. The TB-IDT also utilizes multiple-frequency, multidirectional, and multi-amplitude accessibility eliminates the false-negatives and the positives, leading to higher and better sensitivity. The designed biosensor produces instantaneous diagnostic results and is highly sensitive in terms of broader bandwidth.
Potential Applications:
This device can be used for on-site testing for diagnostics making it analogous to a preliminary disease detection utilized by millions around the world.
Advantages and Benefits:
Unlike conventional SAW-grade sensors, the developed sensor is highly sensitive, selective, reproducible, robust, requires low cost and maintenance and comes with capability of instantaneous diagnostic results and thus, making it a point-of-care biosensor. Additionally, the POC biosensor is capable of detection of multiple analytes of different disease biomarkers. The designed biosensor produces instantaneous diagnostic results and is highly sensitive in terms of broader bandwidth as compared to conventional SAW-grade biosensors. The designed invention also has better and more sensitive coda waves, vital for feature extraction leading to higher sensitivity. This invention is also very economical and applicable to multiple different diseases and future outbreaks.