Search Results - Biomedical+and+Life+Sciences

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Abbapolins as Inhibitors and Degraders of Polo-Like Kinases
Reference #: 01593 The University of South Carolina is offering licensing opportunities for Abbapolins as Inhibitors and Degraders of Polo-Like Kinases Background: There are no effective treatments for castration-resistant prostate cancers as all current therapies eventually fail. Invention Description: Novel chemicals called abbapolins are described...
Published: 9/14/2022   |   Inventor(s): Campbell Mcinnes, Michael Wyatt, Danda Chapagai, Jessy Stafford, Gursanker Ramamoorthy
Keywords(s): abbapolin, drug discovery, peptide, Polo Like Kinase
Category(s): Biomedical and Life Sciences, Health Sciences
Phospholipid Presenting Particles for Cell Targeting in Therapy and Diagnostics
Reference #: 01594 The University of South Carolina is offering licensing opportunities for Phospholipid Presenting Particles for Cell Targeting in Therapy and Diagnostics Background: Current FDA approved controlled/extended-release formulations based on polyesters such as polylactic acid, poly(lactide-co-glycolide), and polycaprolactone do not benefit...
Published: 9/13/2022   |   Inventor(s): Kidochukwu Atube, Robert Gower
Keywords(s): cell targeting, drug delivery, emulsion, microparticles, phospholipid, poly(lactide-co-glycolide), polymer particles
Category(s): Biomedical and Life Sciences, Health Sciences
Panaxynol as a new agent for cancer prevention and treatment
Reference #: 01618 The University of South Carolina is offering licensing opportunities for Panaxynol as a new agent for cancer prevention and treatment Background: National costs for cancer care were estimated to be $208.9 billion in 2020; particularly for colorectal cancer (CRC), the economic burden in the U.S. is estimated to be over $24 billion...
Published: 9/12/2022   |   Inventor(s): Elizabeth Murphey, Lorne Hofseth
Keywords(s): cancer, cancer prevention, cancer treatment, Colon cancer, Natural product, polyps
Category(s): Biomedical and Life Sciences, Health Sciences
Water based hypotonic lysis method for Adeno Associated Virus purification
Reference #: 01595 The University of South Carolina is offering licensing opportunities for a hypotonic-solution-based cell lysis method for Adeno Associated Virus purification Background: Adeno Associated Viral vectors have become popular candidates for gene therapy but suffer the drawback of requiring a time-consuming freeze-thaw (FT) lysis or...
Published: 9/12/2022   |   Inventor(s): Sujit Pujhari, Ronald Smithwick
Keywords(s): adeno associated virus, gene therapy, hypotonic solution, solute concentration, viral vectors, water potential
Category(s): Health Sciences, Biomedical and Life Sciences
Temperature Responsive Cell Culture Platform for Mechanobiological Manipulation
Reference #: 01436 The University of South Carolina is offering licensing opportunities for Temperature Responsive Cell Culture Platform for Mechanobiological Manipulation Background: The invention pertains to a swellable platform with surface microwells of various shapes that can encapsulate and systematically apply mechanical pressure on cells....
Published: 9/4/2022   |   Inventor(s): Ehsan Jabbarzadeh, Christopher Wu
Keywords(s): Antigen uptake, Cell culture platform, Cell secretome, Cellular Engineering, drug delivery, drug discovery, Gene transfection, Intracellular delivery, Mechanobiology, Mechanostimulation, PNIPAM
Category(s): Health Sciences, Biomedical and Life Sciences, Chemistry and Biochemistry
Tyrosine and resveratrol derivatives as novel modulators of cellular serine-ADP-ribosylation
Reference #: 01578 The University of South Carolina is offering licensing opportunities for Tyrosine and resveratrol derivatives as novel modulators of cellular serine-ADP-ribosylation Background: Currently, there are no molecules that specifically inhibit only serine-ADP-ribosylation without affecting global ADP-ribosylation. Invention Description: We...
Published: 8/30/2022   |   Inventor(s): Sajish Mathew
Keywords(s): PARP inhibitors
Category(s): Health Sciences, Biomedical and Life Sciences
Use of delta 8 THC to treat inflammatory and autoimmune diseases
Reference #: 01583 The University of South Carolina is offering licensing opportunities for Use of delta 8 THC to treat inflammatory and autoimmune diseases Background: There are millions of people who suffer from debilitating inflammatory and autoimmune diseases against which there is no cure. Delta-8 THC is present in small quantity in cannabis...
Published: 8/9/2022   |   Inventor(s): Prakash Nagarkatti, Mitzi Nagarkatti, Khadija Kakar
Keywords(s): anti-inflammatory biotech, anti-inflammatory pharma, autoimmune diseases, cannabinoids, inflammation
Category(s): Biomedical and Life Sciences, Health Sciences
2-Hydroxyglutarate Enantiomer Detection in Complex I Deficient Encephalopathy
Reference #: 01572 The University of South Carolina is offering licensing opportunities for 2-Hydroxyglutarate Enantiomer Detection in Complex I Deficient Encephalopathy Background: There are genetic diseases that impair the function of the mitochondria, they do not make enough ATP (energy) for demanding tissues such as the brain and muscles. One...
Published: 8/8/2022   |   Inventor(s): Norma Frizzell
Keywords(s): 2-hydroxyglutarate, electron transport chain, enantiomer, Leigh Syndrome, metabolic flexibility, metabolite, mitochondria, mitochondrial disease
Category(s): Health Sciences, Biomedical and Life Sciences
Novel Resuscitative fluid for Trauma Patients
Reference #: 00444 The University of South Carolina is offering licensing opportunities for a novel IV fluid to stabilize victims of severe blood loss and hasten recovery without complications in order to reduce stays in intensive care, lower the incidence of pneumonia, and generally cut costs associated with treating victims of hemorrhagic shock....
Published: 6/9/2022   |   Inventor(s): Stephen Fann, Michael Yost, James Morrison
Keywords(s):  
Category(s): Health Sciences, Biomedical and Life Sciences
The preparation of a brain targeted artificial nano-enzyme and application
Reference #: 01514 The University of South Carolina is offering licensing opportunities for The preparation of a brain targeted artificial nano-enzyme and application Background: Chronic neuroinflammation is caused by the activation of microglia, which is the major cause of central neuronal system (CNS) diseases, including Alzheimer’s disease,...
Published: 6/9/2022   |   Inventor(s): Peisheng Xu, Haijun Liu
Keywords(s): Alzheimer’s disease, Amyotrophic lateral sclerosis, brain injury, Brain targeted nanoparticle, Brain tumor, Epilepsy, frontotemporal dementia, glioblastoma, Huntington's disease, Multiple sclerosis, neonatal hypoxic-ischemic, neuroblastoma, Parkinson's disease, post-traumatic stress disorder, Spinal cord injury, stroke
Category(s): Nanotechnology, Health Sciences, Biomedical and Life Sciences
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