Minimally Invasive and Semi-Automated Myocardial Injection Device


Reference #: 01450

The University of South Carolina is offering licensing opportunities for Minimally Invasive and Semi-Automated Myocardial Injection Device


Approximately, 550,000 first episodes and 200,000 recurrent episodes of acute myocardial infarction occur annually.

Invention Description:

This device is designed and optimized to perform automated and minimally invasive intramyocardial injections for cardiac repair. Our technology eliminates the need for opening of chest cavity for injections of therapeutics to the heart muscle after heart attack, can detect the diseased tissue and deliver a specified volume of a therapeutic biomaterial to the region of interest.

Potential Applications:

Currently, approaches to trans-epicardial intramyocardial injection therapy include invasive surgery to gain access to the diseased (targeted) section of the heart wall. Utilizing this technology will help clinicians to perform injection- based cardiac repair using a minimally invasive approach based on a semi-automated medical device.

Advantages and Benefits: 

This technology will significantly lower the costs by eliminating the need for invasive surgery. After approval for clinical trials can perform this procedure faster with reduced recovery time for treated patients and can potentially lower intra-operative risk due to invasive surgery. It will also simplify the process for clinicians by outsourcing some detection and infusion steps with use of computers and control systems.

Patent Information:
Title App Type Country Serial No. Patent No. File Date Issued Date Expire Date Patent Status
Minimally Invasive and Semi-Automated Myocardial Injection Device PCT United States PCT/US2021/50184   9/14/2021     Filed
For Information, Contact:
Technology Commercialization
University of South Carolina
Francis Spinale
Tarek Shazly
Dara Azar Ahmadi
Heather Trainor
automatic infusion
automatic needle
cardiac repair
Injection device
intramyocardial injection therapy
medical device
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