Persistent Micelle Corona Chemistry


Reference #: 01535

The University of South Carolina is offering licensing opportunities for Persistent Micelle Corona Chemistry


Polymer micelles have found significant uses in areas such as drug/gene delivery, medical imaging, and as templates for nanomaterials. For many of these applications, the micelle performance depends on its size and chemical functionalization. To date, however, these parameters have often been fundamentally coupled since the equilibrium size of a micelle is a function of the chemical composition in addition to other parameters.

Invention Description:

This processing concept enables one to independently adjust the chemistry and size of micelles. The essence is that if the size can be preserved (i.e. persistent) then the chemistry is a degree of freedom.

Potential Applications:

Drug delivery, polyelectrolyte membranes

Advantages and Benefits:

This approach uniquely enables series of micelles where the size is held constant (important for cell penetration) and all aspects of the corona chemistry are independently adjustable.

Patent Information:
For Information, Contact:
Technology Commercialization
University of South Carolina
Morgan Stefik
Taylor Larison
drug delivery
drug delivery pharma
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